2019FBIC 聚焦烘焙食品中的“丙烯酰胺”：定时炸弹还是新机遇？ 潘玉，帝斯曼

2020-03-01 132浏览

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  • 12.! ! ! 2016 HC ! ! 65 “ ! ! FDA ” ‘if 2/3 slide 31 acrylamide is in a consumer product, the consumer must be warned’.Source:https://www.canada.ca/en/health-canada/services/food-nutrition/public-involvement-partnerships/comments-received-effectiveness-acrylamide-reduction12strategies-food-summary.html
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  • 15.Fisher 344 Fisher 344 / B6C3F 2 F344 / N 1986 Johnson et al. Toxicol Appl Pharmacol 85:154-168 1989 He et al. Scand J Work Environ Health 15:125-129 1995 Friedman et al. Fundam Appl Toxicol 27:95-105 2001 Granath et al.. Occup Environ Med 58:608-609. 2001 Hagmar et al. Scand J Work Environ Health 27:219-226 2005 Fennell et al. Toxicol Sci 85:447-459 2006 Ruhr et al. Cancer Epidemiol Biomarkers Prev 15:266-271 2008 LoPachin and Gavin. J. Agric Food Chem 56:5994-6003 2012 Viswanath Indian J Med Res 135:795-796. 2013 Beland et al. Food Chem Toxicol 51:149-159.
  • 16.AA Hogervorst et al AA AA 10µgAad-1 1.98 AA HR 10 AA 2.7 AA 2007 Wilson et al 2010 Bongers et al 2012 Olesen et al 2008 Olesen et al 2012 2589 Cancer Epidermiol Biomarkers Prev 16:2313-2322 88,672 Cancer Epidermiol Biomarkers Prev 19:2503-2515 PLoS One 7:e38016 / 374 374 24,697 Int J Cancer 122:2094-2100 Toxicology 296:67-72
  • 17.MOE exposures • • Margins of 10,000 3 3 2 3 3 2 The EFSA has estimated dietary AA exposure based on mean food contents of 10,366 results from 24 European countries in 2007-2009 and national consumption data. 1Source:1 EFSA, Update on acrylamide levels in food from monitoring years 2007 and 2010 (2012)
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  • 20.• • • • GSH GSH • WHO/FAO) 6-12 1-3 2012 2013 111 N =302 • 7.5 12.4μg/kg BW/day • Mojska et al (2012) Food and Chemical Toxicity 50: 2722-2728 • 0.06,1.43 6.41μg/ kg BW /day • 3-5 Cengiz and Gϋndϋz (2013) Food and Chemical Toxicology 60:514519Source:Erkekoğlu and Baydar (2010) Toxicity of acrylamide and evaluation of its exposure in baby foods. Nutrition Research Review 23, 323-333.
  • 21.• • SGA 2012 2013 2016 2006 - 2010 / N=1101 / N = 50,651 • -0.33cm • SGA Pedersen et al. (2012) Environmental Health Perspectives 120(12): 1739-1745. 10 1.11 OR -25.7g • • SGA TDS N = 1471 • -132g; SGA Cohort Duarte-Salles et al. (2013) Environ Health Perspect 121: 371-379 19.2μg/ 10μg/ 1.11 -0.05cm -9.8 g SGA Kadawathagedara et al. (2016) Environmental Research 149:189-196
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  • 24.0 1 1 2 FDE ! ! ! ! ! Page 24 FDE FoodDrinkEurope 2014.http://ec.europa.eu/food/safety/chemical_safety/contaminants/catalogue/acrylamide_en
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  • 31.‘ Haitai - Tomato Flavoured Potato Snack 2011, Korea ’ ‘ Mondelez-Cheese & Onion Flavour Potato and Wheat Chips 2017, Canada Mondelez- Chocolate Flavoured Soft Chunky Cookies 2016, Canada Page 31 Mondelez - Wafers 2017, Canada ’ Mondelez-Dill & Onion Flavour Potato & Wheat Crackers 2017, Canada Frito-Lay BBQ & Chili Flavoured Tortilla Chips 2017, Canada Mondelez-Peanut Butter Cereal Biscuits 2016, Canada Christie Honey Maid – Crumbs premix 2017, Canada
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  • 35.Cindy.Pan@dsm.com