utilities.py 文件源码

python
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项目:SCaIP 作者: simonsfoundation 项目源码 文件源码
def extract_DF_F(Y, A, C, i=None):
    """Extract DF/F values from spatial/temporal components and background

     Parameters
     -----------
     Y: np.ndarray
           input data (d x T)
     A: sparse matrix of np.ndarray
           Set of spatial including spatial background (d x K)
     C: matrix
           Set of temporal components including background (K x T)

     Returns
     -----------
     C_df: matrix
          temporal components in the DF/F domain
     Df:  np.ndarray
          vector with baseline values for each trace
    """
    A2 = A.copy()
    A2.data **= 2
    nA2 = np.squeeze(np.array(A2.sum(axis=0)))
    A = A * diags(1 / nA2, 0)
    C = diags(nA2, 0) * C

    # if i is None:
    #    i = np.argmin(np.max(A,axis=0))

    Y = np.matrix(Y)
    Yf = A.transpose() * (Y - A * C)  # + A[:,i]*C[i,:])
    Df = np.median(np.array(Yf), axis=1)
    C_df = diags(1 / Df, 0) * C

    return C_df, Df
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