core.py 文件源码

def flip_jxn(jxn, gs1):
    '''Flip jxn orientation for RNA Fusion that is inverse according to strand info'''
    chrom1, pos1, str1, chrom2, pos2, str2, repleft, repright = re.split(':', jxn)
    chrom1 = str(chrom1)
    chrom2 = str(chrom2)
    pos1 = int(pos1)
    pos2 = int(pos2)
    if str1 != gs1[0]:
        flip = 1
        flipstr = maketrans("-+", "+-")
        if str1 == "-":
            new_pos1 = chrom1 + ":" + str(pos1) + ":" + str1.translate(flipstr)
        else:
            new_pos1 = chrom1 + ":" + str(pos1) + ":" + str1.translate(flipstr)
        if str2 == "-":
            new_pos2 = chrom2 + ":" + str(pos2) + ":" + str2.translate(flipstr)
        else:
            new_pos2 = chrom2 + ":" + str(pos2) + ":" + str2.translate(flipstr)
        newid = new_pos2 + ":" + new_pos1 + ":" + str(repright) + ":" + str(repleft)
    else:
        newid = jxn
        flip = 0
    return (newid, flip)