run_wei.py 文件源码

def fit_koff(nmax=523, NN=4e8, **params):
    tbind = params.pop("tbind")
    params["kd"] = 1e9/tbind
    dx = params.pop("dx")
    rw = randomwalk.get_rw(NAME, params, setup=setup_rw, calc=True)
    rw.domains[1].dx = dx
    times = draw_empirically(rw, N=NN, nmax=nmax, success=False)
    bins = np.logspace(np.log10(min(times)), np.log10(max(times)), 35)
    #bins = np.logspace(-3., 2., 35)
    hist, _ = np.histogram(times, bins=bins)
    cfd = np.cumsum(hist)/float(np.sum(hist))
    t = 0.5*(bins[:-1] + bins[1:])
    tmean = times.mean()
    toff = NLS(t, cfd, t0=tmean)
    koff = 1./toff
    return dict(t=t, cfd=cfd, toff=toff, tmean=tmean, koff=koff)

##### run rw in collect mode and draw bindings from empirical distributions